Director/Senior Director, Marketing Operations & Meetings

About Stoke

Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study. Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico; Biogen receives exclusive rest of world commercialization rights

STK-002 is Stoke’s proprietary antisense oligonucleotide (ASO) in clinical development for the treatment of autosomal dominant optic atrophy (ADOA), the most common inherited optic nerve disorder. STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals.

Stoke’s initial focus is on diseases of the central nervous system and the eye that are caused by a loss of ~50% of normal protein levels (haploinsufficiency). Proof of concept has been demonstrated in other organs, tissues, and systems, supporting broad potential for the Company’s proprietary approach.

Position Purpose

The Director/Senior Director, Marketing Operations& Meetings will be a key member of the Commercial organization, responsible for enabling operational excellence across marketing, field, and event execution. This role will own critical systems and processes that ensure compliant, efficient, and high-quality delivery of marketing and commercial initiatives, including the Promotional Review Committee / Medical Legal Review (PRC/MLR) process, print and inventory management, standard operating procedures (SOPs), and conference strategy and execution.

The successful candidate will combine operational precision with creative problem solving, ensuring seamless coordination across functions—including Regulatory, Legal, Compliance, Medical Affairs, and Sales—to drive the company’s strategic objectives and support launch readiness. This position reports to the Vice President, Sales & Marketing.

Key Responsibilities

• Lead PRC/MLR Operations:
• Facilitate review meetings, manage agendas, track status, and ensure timely approvals for all promotional, medical, and corporate materials.
• Partner with Regulatory and Legal teams to ensure compliance with FDA and OPDP requirements.
• Oversee Veeva Vault process design, implementation, and continuous optimization.
• Develop and maintain PRC policies and best practices to ensure efficiency and compliance.
• Marketing Operations Infrastructure:
• Manage print and inventory systems, ensuring timely production, fulfillment, and distribution to field teams.
• Oversee third-party vendor relationships, including warehouse management, promotional materials production, and online ordering platforms.
• Establish and document business rules, workflows, and operational guidelines across marketing and sales teams.
• Track and report key performance indicators (KPIs) for operational effectiveness and program ROI.
• Meetings, Congresses, and Speaker Programs:
• Develop and execute the company’s annual congress and conference strategy in partnership with Medical Affairs, Marketing, and Sales.
• Secure exhibit space, sponsorships, and logistics for major conferences and professional society meetings.
• Oversee conference booth design, asset development, and on-site coordination.
• Support the planning and execution of promotional speaker programs and related logistics.
• Cross-Functional Collaboration:
• Serve as a key liaison between Marketing, Medical Affairs, Compliance, and Field Operations to ensure alignment and operational readiness.
• Champion process improvement initiatives and operational excellence across commercial teams.
• Drive consistent implementation of brand standards, compliance policies, and internal controls.

Required Skills & Experience

• Bachelor’s degree required; advanced degree preferred.
• Minimum 10 years of marketing operations experience in the biopharmaceutical industry, with a strong understanding of PRC/MLR and commercial compliance.
• Proven expertise with Veeva Vault and related promotional review systems.
• Experience managing speaker programs, scientific conferences, or medical meetings.
• Strong understanding of pharmaceutical promotional regulations and best practices.
• Demonstrated success managing external agencies, vendors, and complex projects.
• Excellent communication, organization, and cross-functional collaboration skills.
• Ability to lead without authority and influence teams across multiple functions.
• Thrives in a fast-paced, dynamic, startup environment where adaptability and initiative are essential.

Location(s)

Stoke is located in Bedford, MA, and will be moving to a new location in Waltham, MA by the end of 2026. This position is field-based, currently based in Bedford and will later be based in Waltham.

Travel

This position will require approximately 20% travel.

Compensation & Benefits

At Stoke Therapeutics, we are committed to offering a comprehensive, competitive and thoughtfully designed total rewards program.

The anticipated salary range for this role at Director level is $230,000 - $252,000 and at the Senior Director level is $265,000 - $291,000. The final offer will be determined based on a variety of factors, including role scope, experience and qualifications, education, market benchmarks, internal equity, and geographic location. In addition to base salary, Stoke offers an annual bonus and equity participation.

Our benefits package includes medical, dental and vision insurance; life, long- and short-term disability insurance; paid parental leave; a 401K plan with company match, unlimited vacation time, tuition assistance and participation in our Employee Stock Purchase Program (ESPP).

Culture & Values

At Stoke, we believe that innovation, the ability to successfully advance our ground-breaking science and having fun as a team are enhanced by being together in person, at least periodically. We allow for flexibility in work arrangements that balance individual’s needs and preferences with the needs of our business and our desire to foster a culture of collaboration and innovation.

Our values guide our work to deliver meaningful medicines for people who need them. We are committed to being true to ourselves, to our colleagues, and to the people with severe diseases who are counting on us. We embrace diversity within a unique culture that is defined by our values. Our employee-led Diversity, Inclusion, and Belonging (DIB) Committee underscores the importance of DIB to who we are and what we do.

Interested candidates: Please visit Stoke’s website to learn more and apply directly to the position listed on our Career Center:

https://www.stoketherapeutics.com/careers/

For more information, visit https://www.stoketherapeutics.com/.

All applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, physical or mental disability or protected veteran status.

Stoke participates in E-Verify.